Staff Publication

A UK prospective multicentre decision impact, decision conflict and economic evaluation of the 21-gene assay in women with node+ve, hormone receptor+ve, HER2-ve breast cancer (2024)

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Type of publication:
Journal article

Author(s):
Holt, Simon; Verrill, Mark; *Pettit, Laura; Rigg, Anna; Hickish, Tamas; Archer, Caroline; Dent, Jo; Dillon, Marianne; Nathan, Mark; Barthelmes, Ludger; Rehman, Shazza; Sharaiha, Yousef; Innis, Paige; Sai-Giridhar, Priya; Khawaja, Saira.

Citation:
British Journal of Cancer. 2024 Feb 02.

Abstract:
BACKGROUND: For a tumour profiling test to be of value, it needs to demonstrate that it is changing clinical decisions, improving clinical confidence, and of economic benefit. This trial evaluated the use of the Oncotype DX Breast Recurrence Score R assay against these criteria in 680 women with hormone receptor-positive (HR+), HER2-negative early breast cancer with 1-3 lymph nodes positive (LN+) in the UK National Health Service (NHS). METHODS: Prior to receipt of the Recurrence Score (RS) result, both the physician and the patient were asked to state their preference for or against chemotherapy and their level of confidence on a scale of 1-5. Following receipt of the RS result, the physician and patient were asked to make a final decision regarding chemotherapy and record their post-test level of confidence. RESULTS: Receipt of the RS result led to a 51.5% (95% CI, 47.2-55.8%) reduction in chemotherapy, significantly increased the relative and absolute confidence for both physicians and patients and led to an estimated saving to the NHS of 787 per patient. CONCLUSION: The use of the Oncotype DX assay fulfils the criteria of changing clinical decisions, improving confidence and saving money.

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An overview of exertional leg pain in the athlete (2024)

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Type of publication:
Journal article

Author(s):
*Crooks S.A.; *Paavana T.; *Heaver C.

Citation:
Orthopaedics and Trauma. 38(1) (pp 56-64), 2024. Date of Publication: February 2024.

Abstract:
Exertional leg pain is a common problem in the athletic population, presenting with a constellation of similar symptoms. Delayed or incorrect diagnosis and treatment may result in significant morbidity and avoidable cessation of activity. Multiple causes such as chronic exertional compartment syndrome (CECS), medial tibial stress syndrome (MTSS), nerve or vascular entrapment syndromes may be responsible. A thorough history and focused clinical examination is mandated, and may yield clues as to the definitive diagnosis. Investigative adjuncts include imaging, compartment pressure measurement and electrodiagnostic studies. Whilst specific management depends on the underlying cause, the mainstay of initial management is activity modification, with surgery reserved for those who fail to respond to conservative measures.

A QIP on the completion of the AMHT Form in the Emergency Department in SaTH (2024)

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Type of publication:
Service improvement case study

Author(s):
*Kallum Claire

Citation:
SaTH Improvement Hub, April 2024

Abstract:
I aim to improve completion of the adult mental health triage form in SaTH ED by 20% by 31/05/2023 through the use of a poster, which will highlight the necessity of completion as well as serving as a reminder for staff to complete paperwork in the correct manner.

Link to full-text

Improvement to assessment and provision of analgesia for patients with suspected Neck of Femur Fracture in ED (2023)

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Type of publication:
Service improvement case study

Author(s):
*Oleg Lujanschi

Citation:
SaTH Improvement Hub, November 2023

Abstract:
To improve the assessment and provision of analgesia (where required) for patients presenting in ED with a suspected Neck of Femur Fracture to ensure all patients meet the national standard by 15 December 2023. Additionally, the aim is to improve the percentage of patients who receive an x-ray when presenting to ED with a suspected Neck of Femur Fracture in line with the national standard of 90 minutes by 15 December 2023.

Link to PDF poster

Improved efficiency and safety Drugs Trolley- Ward 27 Getting to Good: Fundamentals in Care (2023)

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Type of publication:
Service improvement case study

Author(s):
*Layla Brice

Citation:
SaTH Improvement Hub, December 2023

Abstract:
To improve the drugs round process to facilitate improved patient care. Standardisation of ward 27 drugs trolley to focus on improving patient and staff experience by the end of January 2023

Link to PDF poster

Sustainable QR solutions for patient information (2023)

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Type of publication:
Service improvement case study

Author(s):
*Umesh Parampalli *Ruchir Mashar *Jefferson George *Anchal Gupta *Florence Quarshie

Citation:
SaTH Improvement Hub, December 2023

Abstract:
To improve patient access to up-to-date and accurate healthcare information by the start of December 2023. A secondary aim was to use a sustainable approach to achieve this.

Link to PDF poster