Type of publication:
Conference abstract
Author(s):
Maybury, B. D.; James, L.; Chadderton, N.; Dowds, J.; Venkatadasari, I.; Riley, J.; Qureshi, I.; Talbot, G.; Giles, H. V.; Phillips, N. J.; Gonzalez, M. Vega; Rakesh, P.; Haslam, A.; Davies, D.; Moosai, S.; Lane, S. A.; *Shenouda, A.; Cherian, G. V.; Kaudlay, P. K.;Starczynski, J.; et al
Citation:
Hematological Oncology, June 2023 Supplement 1; 41: 205-207.
Abstract:
Link to full-text [OpenAthens account required]
Type of publication:
Journal article
Author(s):
*Baker, Jacob; Denning, David W.
Citation:
British Medical Bulletin. 147(1):62-78, 2023 Sep 12.
Abstract:
INTRODUCTION: Fungal disease has historically presented a diagnostic challenge due to its often non-specific clinical presentations, relative infrequency and reliance on insensitive and time-intensive fungal culture. SOURCES OF DATA: We present the recent developments in fungal diagnostics in the fields of serological and molecular diagnosis for the most clinically relevant pathogens; developments that have the potential to revolutionize fungal diagnosis through improvements in speed, simplicity and sensitivity. We have drawn on a body of evidence including recent studies and reviews demonstrating the effectiveness of antigen and antibody detection and polymerase chain reaction (PCR) in patients with and without concurrent human immunodeficiency virus infection. AREAS OF AGREEMENT: This includes recently developed fungal lateral flow assays, which have a low cost and operator skill requirement that give them great applicability to low-resource settings. Antigen detection for Cryptococcus, Histoplasma and Aspergillus spp. are much more sensitive than culture. PCR for Candida spp., Aspergillus spp., Mucorales and Pneumocystis jirovecii is more sensitive than culture and usually faster. AREAS OF CONTROVERSY: Effort must be made to utilize recent developments in fungal diagnostics in clinical settings outside of specialist centres and integrate their use into standard medical practice. Given the clinical similarities of the conditions and frequent co-infection, further study is required into the use of serological and molecular fungal tests, particularly in patients being treated for tuberculosis. GROWING POINTS: Further study is needed to clarify the utility of these tests in low-resource settings confounded by a high prevalence of tuberculosis. AREAS TIMELY FOR DEVELOPING RESEARCH: The diagnostic utility of these tests may require revision of laboratory work flows, care pathways and clinical and lab coordination, especially for any facility caring for the immunosuppressed, critically ill or those with chronic chest conditions, in whom fungal disease is common and underappreciated.
Link to full-text [open access - no password required]
Altmetrics:
Type of publication:
Journal article
Author(s):
Al-Tawil, Mohammed; Muscogliati, Eduardo; Jubouri, Matti; Saha, Priyanshu; *Patel, Ravi; Mohammed, Idhrees; Bailey, Damian M; Williams, Ian M; Bashir, Mohamad
Citation:
Expert Review of Medical Devices. 1-8, 2023 Jun 16
Abstract:
INTRODUCTION: Endovascular aneurysm repair (EVAR) has rapidly become the preferred management of abdominal aortic aneurysm (AAA). Sac regression status post-EVAR has been linked to clinical outcomes as well as the choice of EVAR device. The aim of this narrative review is to investigate the relationship between sac regression and clinical outcomes post-EVAR in AAA. Another aim is to compare sac regression achieved with the main EVAR devices. AREAS COVERED: We carried out a comprehensive literature search on multiple electronic databases. Sac regression was usually defined as a decrease in the sac diameter (>10 mm) over follow-up. This revealed that individuals who had sac regression post-EVAR had significantly lower mortality, and higher event-free survival rates. Further, lower rates of endoleak and reintervention were observed in patients with regressing aneurysm sacs. Sac regression patients also had significantly lower odds of rupture compared to counterparts with stable or expanded sacs. The choice of EVAR device was also shown to impact regression, with the Fenestrated Anaconda showing favorable results. EXPERT OPINION: Sac regression post-EVAR in AAA is an important prognostic factor as it translates to improved mortality and morbidity. Therefore, this relationship must be seriously taken into consideration during follow-up.
Altmetrics:
Type of publication:
Service improvement case study
Citation:
SaTH Improvement Hub, 2023
Abstract:
Multi Agency Discharge Events (MADEs) are held to work with internal and external partners across the Integrated Care System to maximise discharges to provide capacity in the acute setting. This case study focuses on the outcomes at RSH.
Link to PDF poster [no password required]
Type of publication:
Service improvement case study
Citation:
SaTH Improvement Hub, 2023
Abstract:
Multi Agency Discharge Events (MADEs) are held to work with internal and external partners across the Integrated Care System to maximise discharges to provide capacity in the acute setting. This case study focuses on the outcomes at PRH
Link to PDF poster [no password required]
Type of publication:
Service improvement case study
Citation:
SaTH Improvement Hub, 2023
Abstract:
Multi Agency Discharge Events (MADEs) are held to work with internal and external partners across the Integrated Care System to maximise discharges to provide capacity in the acute setting.
Link to PDF poster [no password required]
Type of publication:
Service improvement case study
Citation:
SaTH Improvement Hub, 2023
Abstract:
As part of the 8 MADEs for 2023 the first focus will be in time for the February half term starting 20th February 2023. The focus for this event will be on patients who are suitable for the virtual wards.
Link to PDF poster [no password required]
Type of publication:
Service improvement case study
Author(s):
*Dr. Sairah Anjum (FY2)
Citation:
SaTH Improvement Hub, May 2023
Abstract:
Guidance was recently approved and uploaded to the SaTH intranet (early April 2023), stating that high risk NOF fracture patients or those unable to tolerate oral bisphosphonates are more likely to benefit from a single 4mg infusion of zoledronic acid followed by 2 weeks of calcium & Vitamin D supplementation, with an overall aim of increasing bone density and reducing risk of further fragility fractures by ~50% by 10th May 2023.
Link to PDF poster [no password required]
Type of publication:
Service improvement case study
Author(s):
*Ward 27 team, *PJF, and *Medicine Ops
Citation:
SaTH Improvement Hub, 2022
Abstract:
Following the August 2022 MADE event it was recognised that ward 27 had significant challenges regarding super stranded and number of medically fit patients. They also have one of the largest bed bases in the trust. A support week was implemented to understand the root cause of these challenges.
Link to PDF poster [no password required]
Type of publication:
Service improvement case study
Author(s):
*Kev Malton
Citation:
SaTH Improvement Hub, May 2023
Abstract:
To improve the use of Teletracking for wards and clinical areas when ordering stock from the Medical Devices Library by 10 May 2023.
Link to PDF poster [no password required]
Shrewsbury and Telford Hospital NHS Trust has an active Research and Innovation Department.
Find out more by visiting either the R&I Intranet pages (only available on a Trust PC) or the R&I pages on the SaTH website.
Shrewsbury and Telford Hospital NHS Trust has an active Improvement Hub.
Find out more by visiting either the Improvement Hub Intranet pages (only available on a Trust PC) or the Improvement Hub page on the SaTH website.